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Article

Identification of the reactive cysteine residues in yeast dipeptidyl peptidase III.

Biochimie - 1 Jan 2010

Jajcanin-Jozić Nina, Deller Sigrid, Pavkov Tea, Macheroux Peter, Abramić Marija

Abstract excerpt

Dipeptidyl peptidases III (DPPs III) form a distinct metallopeptidase family characterized by the unique HEXXGH motif. High susceptibility to inactivation by organomercurials suggests the presence of a reactive cysteine residue(s) in, or close to, their active site. Yeast DPP III contains five Cys, none of which is absolutely conserved within the family. In order to identify reactive residue(s), site-directed...

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PMID: 19825391
DOI: 10.1016/j.biochi.2009.09.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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