Article
Role of cysteine residues in thiol modification of acyl-CoA:diacylglycerol acyltransferase 2 from yeast.
Biochemistry - 20 Apr 2010
Liu Qin, Siloto Rodrigo M P, Weselake Randall J
Abstract excerpt
Acyl-CoA:diacylglycerol acyltransferase (EC 2.3.1.20, DGAT or DAGAT), which catalyzes the final step in triacylglycerol biosynthesis, has at least two discrete family members (DGAT1 and DGAT2) with different physiological roles. Here we report a systematic study of the local functional and structural role of seven cysteine residues present in DGAT2 from Saccharomyces cerevisiae (ScDGAT2, also known as Dga1p)...
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