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Article

Metabolomics approaches for discovering biomarkers of drug-induced hepatotoxicity and nephrotoxicity.

Toxicology and applied pharmacology - 1 Mar 2010

Beger Richard D, Sun Jinchun, Schnackenberg Laura K

Abstract excerpt

Hepatotoxicity and nephrotoxicity are two major reasons that drugs are withdrawn post-market, and hence it is of major concern to both the FDA and pharmaceutical companies. The number of cases of serious adverse effects (SAEs) in marketed drugs has climbed faster than the number of total drug prescriptions issued. In some cases, preclinical animal studies fail to identify the potential toxicity of a new chemical...

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Identifiers

PMID: 19932708
DOI: 10.1016/j.taap.2009.11.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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