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Article

Ingenuity pathways analysis of urine metabonomics phenotypes toxicity of gentamicin in multiple organs.

Molecular bioSystems - 1 Oct 2010

Lv Haitao, Liu Lian, Zhang Yingzhi, Song Ting, Lu Juan, Chen Xi

Abstract excerpt

We introduce the use of Ingenuity Pathway Analysis to analyzing global metabonomics in order to characterize phenotypically biochemical perturbations and the potential mechanisms of the gentamicin-induced toxicity in multiple organs. A single dose of gentamicin was administered to Sprague Dawley rats (200 mg/kg, n = 6) and urine samples were collected at -24-0 h pre-dosage, 0-24, 24-48, 48-72 and 72-96 h...

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Identifiers

PMID: 20714645
DOI: 10.1039/c0mb00064g

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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