Article
Plasma multi-omics outlines association of urobilinogen with corticosteroid non-response, inflammation and leaky gut in Sever Alcoholic Hepatitis
2023-03-06
Abstract excerpt
<h4>ABSTRACT</h4> <h4>Background and Aims</h4> Severe alcoholic hepatitis (SAH) has a high mortality and corticosteroid therapy is effective in 60% patients. Reliable indicators of response to therapy and mortality in SAH are needed. A total of 223 SAH patients, 70 in derivative [50 responders (R) and 20 non-responders (NR)] and 153 in validation cohort [136R, 17NR] were subjected to plasma metabolic/meta-proteomi...
Topics
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- Cholangiocarcinoma and Gallbladder Cancer Studies
- Drug-Induced Hepatotoxicity and Protection
- Folate and B Vitamins Research
- Liver Disease Diagnosis and Treatment
- Liver Diseases and Immunity
- Neonatal Health and Biochemistry
- Pediatric Hepatobiliary Diseases and Treatments
- Pharmacogenetics and Drug Metabolism
Identifiers and source
- Literature Corpus work
- 738cfab6-643f-5040-9185-5f118d0f95c5
- DOI
- 10.1101/2023.03.06.23286831
