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Article

MUC7 polymorphisms are associated with a decreased risk of a diagnosis of asthma in an African American population.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Dec 2009

Watson Alan M, Ngor Wai-Man, Gordish-Dressman Heather, Freishtat Robert J, Rose Mary C

Abstract excerpt

PURPOSE: Mucin glycoproteins contribute to lung pathophysiology in asthma. The protein backbone of mucin glycoproteins is encoded by specific MUC genes, which exhibit a high degree of polymorphisms that generate a variable number of tandem repeat (VNTR) domains. MUC7 typically encodes for 6 VNTRs, each with 23 amino acids. In a northern European cohort, a polymorphism encoding MUC7*5 (5-VNTR) is in 100% linkage...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19820409
DOI: 10.2310/JIM.0b013e3181c0466d
PMCID: PMC3326394

Genes

MUC7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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