Association of human leukocyte antigen class II alleles with response to immunosuppressive therapy in Korean aplastic anemia patients.

doi:10.1016/j.humimm.2009.10.002

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Article

Association of human leukocyte antigen class II alleles with response to immunosuppressive therapy in Korean aplastic anemia patients.

Human immunology - 1 Jan 2010

Song Eun Young, Kang Hyoung Jin, Shin Hee Young, Ahn Hyo Seop, Kim Inho, Yoon Sung-Soo, Park Seonyang, Kim Byoung Kook, Park Myoung Hee

Abstract excerpt

HLA-DR15 (DR2) is overrepresented in aplastic anemia (AA) patients, and its presence is associated with a better response to cyclosporine-based immunosuppressive therapy (IST). However, little is known about other human leukocyte antigen (HLA) alleles affecting therapy response. We investigated 37 Korean patients with severe AA for the association of HLA class II alleles with response to IST: cyclosporine A...

Topics

Adolescent
Adult
Aged
Alleles
Anemia, Aplastic
Antilymphocyte Serum
Asian People
Child
Child, Preschool
Cyclosporine
Female
HLA-D Antigens
Humans
Immunosuppressive Agents
Male

Source

Open in PubMed

Identifiers

PMID: 19819281
DOI: 10.1016/j.humimm.2009.10.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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