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Article

The polymorphisms of human leukocyte antigen loci may contribute to the susceptibility and severity of severe aplastic anemia in Chinese patients.

Human immunology - 1 Aug 2014

Wang Min, Nie Neng, Feng Sizhou, Shi Jun, Ge Meili, Li Xingxin, Shao Yingqi, Huang Jinbo, Zheng Yizhou

Abstract excerpt

The human leukocyte antigen (HLA) system has been reported to be involved in the development of aplastic anemia (AA). We compared and analyzed HLA-A, B, C, DRB1 and DQB1 alleles in 96 Chinese severe AA (SAA) patients to those in 600 healthy people chosen randomly from the China Marrow Donor Program to investigate the association of HLA class I and II allele polymorphisms with disposition of SAA and its severity...

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Identifiers

PMID: 24979673
DOI: 10.1016/j.humimm.2014.06.011

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