Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of a common LQT1 mutation in five apparently unrelated families in a regional inherited arrhythmia clinic.

Journal of cardiovascular electrophysiology - 1 Mar 2010

Gray Christopher, Gula Lorne J, Klein George J, Skanes Allan C, Yee Raymond, Sy Raymond, Salisbury Benjamin A, Wong Jorge, Chattha Ishvinder, Subbiah Rajesh N, Krahn Andrew D

Abstract excerpt

BACKGROUND: The Inherited Arrhythmia Clinic at the University of Western Ontario services a catchment area of 1.5 million people and follows families with inherited arrhythmia syndromes. METHODS: Patients referred for evaluation of long-QT Syndrome (LQTS) are evaluated with resting and standing ECGs, and treadmill exercise testing. Patients with findings consistent with LQTS are offered comprehensive genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Incidence

Share to KCNQ1 Potassium Channel

Share to Long QT Syndrome

Share to Ontario

Share to Polymorphism, Single Nucleotide

Share to Young Adult

Source

Identifiers

PMID: 19817925
DOI: 10.1111/j.1540-8167.2009.01626.x

Genes

KCNQ1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of a common LQT1 mutation in five apparently unrelated families in a regional inherited arrhythmia clinic.PMID 19817925Read ↗

Clinical presentation and genetic characterization of early-onset atrial fibrillation in patients affected by long QT syndrome: A single-center experience.Semantic proximity Read ↗

A novel mutation in KVLQT1 is the molecular basis of inherited long QT syndrome in a near-drowning patient's family.Semantic proximity Read ↗

KCNQ1 mutations in patients with a family history of lethal cardiac arrhythmias and sudden death.Semantic proximity Read ↗

Phenotypic variability in Caucasian and Japanese patients with matched LQT1 mutations.Semantic proximity Read ↗

Characterization of a KCNQ1/KVLQT1 polymorphism in Asian families with LQT2: implications for genetic testing.Semantic proximity Read ↗

Risk of syncope in family members who are genotype-negative for a family-associated long-QT syndrome mutation.Semantic proximity Read ↗

Genotype-phenotype correlation in the long-QT syndrome: gene-specific triggers for life-threatening arrhythmias.Semantic proximity Read ↗

KVLQT1 C-terminal missense mutation causes a forme fruste long-QT syndrome.Semantic proximity Read ↗

Homozygous/Compound Heterozygous Triadin Mutations Associated With Autosomal-Recessive Long-QT Syndrome and Pediatric Sudden Cardiac Arrest: Elucidation of the Triadin Knockout Syndrome.Semantic proximity Read ↗

Penetrance and expressivity of the R858H CACNA1C variant in a five‐generation pedigree segregating an arrhythmogenic channelopathySemantic proximity Read ↗

Variable expression of long QT syndrome among gene carriers from families with five different HERG mutations.Semantic proximity Read ↗

Three generations of hereditary long-QT syndrome with complete penetrance caused by the p.G316E KCNQ1 mutation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.