Article
The era of genome-wide association studies: opportunities and challenges for asthma genetics.
Journal of human genetics - 1 Nov 2009
Zhang Guicheng, Goldblatt Jack, LeSouëf Peter
Abstract excerpt
In the era of genome-wide association (GWA) studies, delineating pathogenic asthma genetic pathways has provided both challenges and opportunities. Initial GWA studies on asthma and asthma-like phenotypes provided some successes in terms of ascertaining new potential asthma candidate genes. However, due to asthma having a heterogeneous etiology, replications of these genotype-phenotype association studies are...
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