Article
HLA-DQA1 gene expression profiling in oligoarticular JIA.
Autoimmunity - 1 May 2009
Haas J P, Metzler M, Frank C, Haefner R, Wassmuth R
Abstract excerpt
Polymorphisms in the upstream regulatory region of the HLA class II DQA1 gene are currently defined by 10 different alleles. Two of them carrying a Y-box mutation are associated with susceptibility to oligoarticular juvenile idiopathic arthritis (OA-JIA). We investigated allele-dependent differences in HLA-DQA1 gene expression in OA-JIA patients. In cells from affected joints compared to peripheral blood, gene...
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