Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Aldehyde Dehydrogenase–Expressing Colon Stem Cells Contribute to Tumorigenesis in the Transition from Colitis to Cancer

7 Oct 2009

Abstract excerpt

Patients with chronic ulcerative colitis are at increased risk of developing colorectal cancer. Although current hypotheses suggest that sporadic colorectal cancer is due to inability to control cancer stem cells, the cancer stem cell hypothesis has not yet been validated in colitis-associated cancer. Furthermore, the identification of the colitis to cancer transition is challenging. We recently showed that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer Immunotherapy and Biomarkers
Share to Pancreatic and Hepatic Oncology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19808966
DOI: 10.1158/0008-5472.can-09-1132

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Aldehyde Dehydrogenase–Expressing Colon Stem Cells Contribute to Tumorigenesis in the Transition from Colitis to CancerPMID 19808966Read ↗

Aldehyde Dehydrogenase 1 Is a Marker for Normal and Malignant Human Colonic Stem Cells (SC) and Tracks SC Overpopulation during Colon TumorigenesisSemantic proximity Read ↗

Disruption of the crypt niche promotes outgrowth of mutated colorectal tumor stem cellsSemantic proximity Read ↗

Therapeutic implications of colon cancer stem cellsSemantic proximity Read ↗

Intestinal stem cells and the colorectal cancer microenvironment.Semantic proximity Read ↗

SMAD4 Suppresses WNT-Driven Dedifferentiation and Oncogenesis in the Differentiated Gut EpitheliumSemantic proximity Read ↗

Stem cells and their implications for colorectal cancer.Semantic proximity Read ↗

Colorectal cancer stem cells.Semantic proximity Read ↗

Identification of tumor initiating cells and early marker genes in normal colonic epithelium that lead to neoplastic transformationSemantic proximity Read ↗

Colonic and colorectal cancer stem cells: progress in the search for putative biomarkersSemantic proximity Read ↗

Stem cells: the intestinal stem cell as a paradigmSemantic proximity Read ↗

Human colon cancer stem cells: a new paradigm in gastrointestinal oncology.Semantic proximity Read ↗

Distribution of intestinal stem cell markers in colorectal precancerous lesionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.