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Article

Recurrence in oral and pharyngeal cancer is associated with quantitative MGMT promoter methylation

6 Oct 2009

Abstract excerpt

BACKGROUND: Biomarkers that predict clinical response, tumor recurrence or patient survival are severely lacking for most cancers, particularly for oral and pharyngeal cancer. This study examines whether gene-promoter methylation of tumor DNA correlates with survival and recurrence rates in a population of patients with oral or pharyngeal cancer. METHODS: The promoter methylation status of the DNA repair gene...

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PMID: 19807915
DOI: 10.1186/1471-2407-9-354

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