Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Salivary DNA methylation panel to diagnose HPV-positive and HPV-negative head and neck cancers

23 Sept 2016

Abstract excerpt

Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous group of tumours with a typical 5 year survival rate of <40 %. DNA methylation in tumour-suppressor genes often occurs at an early stage of tumorigenesis, hence DNA methylation can be used as an early tumour biomarker. Saliva is an ideal diagnostic medium to detect early HNSCC tumour activities due to its proximity to tumour site, non-invasiveness...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Head and Neck Cancer Studies
Share to Salivary Gland Disorders and Functions
Share to Salivary Gland Tumors Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27663357
DOI: 10.1186/s12885-016-2785-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Salivary DNA methylation panel to diagnose HPV-positive and HPV-negative head and neck cancersPMID 27663357Read ↗

Promoter Hypermethylation of Tumor-Suppressor Genes p16INK4a, RASSF1A, TIMP3, and PCQAP/MED15 in Salivary DNA as a Quadruple Biomarker Panel for Early Detection of Oral and Oropharyngeal CancersSemantic proximity Read ↗

The use of salivary biomarkers in the detection of oral squamous cell carcinomaSemantic proximity Read ↗

Detection of Promoter Hypermethylation in Salivary Rinses as a Biomarker for Head and Neck Squamous Cell Carcinoma SurveillanceSemantic proximity Read ↗

Tumor-Specific Methylation in Saliva: A Promising Biomarker for Early Detection of Head and Neck Cancer RecurrenceSemantic proximity Read ↗

Salivary DNA Methylation as an Epigenetic Biomarker for Head and Neck Cancer. Part I: A Diagnostic Accuracy Meta-AnalysisSemantic proximity Read ↗

DNA Methylome Distinguishes Oropharyngeal and Oral Cancer from Oral Lesions and Healthy Oral MucosaSemantic proximity Read ↗

Machine Learning-Based Genome-Wide Salivary DNA Methylation Analysis for Identification of Noninvasive Biomarkers in Oral Cancer DiagnosisSemantic proximity Read ↗

Circulating tumour DNA alterations as biomarkers for head and neck cancer: a systematic review.Semantic proximity Read ↗

CpG location and methylation level are crucial factors for the early detection of oral squamous cell carcinoma in brushing samples using bisulfite sequencing of a 13-gene panelSemantic proximity Read ↗

DNA methylation biomarkers in biological fluids for early detection of respiratory tract cancerSemantic proximity Read ↗

The Role of Methylation as an Epigenetic Marker in HPV‐Related Oral LesionsSemantic proximity Read ↗

Genome‐wide DNA methylation profiling in tongue squamous cell carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.