A novel literature-based approach to identify genetic and molecular predictors of survival in glioblastoma multiforme: Analysis of 14,678 patients using systematic review and meta-analytical tools.

doi:10.1016/j.jocn.2014.10.029

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Article

A novel literature-based approach to identify genetic and molecular predictors of survival in glioblastoma multiforme: Analysis of 14,678 patients using systematic review and meta-analytical tools.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 May 2015

Thuy Matthew N T, Kam Jeremy K T, Lee Geoffrey C Y, Tao Peter L, Ling Dorothy Q, Cheng Melissa, Goh Su Kah, Papachristos Alexander J, Shukla Lipi, Wall Krystal-Leigh, Smoll Nicolas R, Jones Jordan J, Gikenye Njeri, Soh Bob, Moffat Brad, Johnson Nick, Drummond Katharine J

Abstract excerpt

Glioblastoma multiforme (GBM) has a poor prognosis despite maximal multimodal therapy. Biomarkers of relevance to prognosis which may also identify treatment targets are needed. A few hundred genetic and molecular predictors have been implicated in the literature, however with the exception of IDH1 and O6-MGMT, there is uncertainty regarding their true prognostic relevance. This study analyses reported genetic...

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PMID: 25698544
DOI: 10.1016/j.jocn.2014.10.029

Genes

IDH1
MGMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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