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Article

Identifying sub-optimal responses to ivermectin in the treatment of River Blindness

18 Sept 2009

Abstract excerpt

Identification of drug resistance before it becomes a public health concern requires a clear distinction between what constitutes a normal and a suboptimal treatment response. A novel method of analyzing drug efficacy studies in human helminthiases is proposed and used to investigate recent claims of atypical responses to ivermectin in the treatment of River Blindness. The variability in the rate at which...

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PMID: 19805362
DOI: 10.1073/pnas.0906176106

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