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Effect of a single dose of 8 mg moxidectin or 150 µg/kg ivermectin on <i>O. volvulus</i> skin microfilariae in a randomized trial: Differences between areas in the Democratic Republic of the Congo, Liberia and Ghana and impact of intensity of infection

2022-02-24

Abstract excerpt

<h4>Background</h4> Community-directed treatment with 150 µg/kg ivermectin (CDTI), the current control strategy, is insufficient for eliminating Onchocerca volvulus transmission across sub-Saharan Africa. Our study in CDTI-naïve areas in Nord Kivu and Ituri (Democratic Republic of the Congo (DRC), Lofa County (Liberia) and Nkwanta district (Ghana) showed that a single 8 mg moxidectin dose reduced skin microfilaria...

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Literature Corpus work
3a06c07f-72b1-55cf-804a-70eb6d497794
DOI
10.1101/2022.02.22.22271335
Open publication

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Effect of a single dose of 8 mg moxidectin or 150 µg/kg ivermectin on <i>O. volvulus</i> skin microfilariae in a randomized trial: Differences between areas in the Democratic Republic of the Congo, Liberia and Ghana and impact of intensity of infectionDOI 10.1101/2022.02.22.22271335
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