Haptoglobin genotypes in Chagas' disease.

doi:10.1016/j.clinbiochem.2009.09.020

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Article

Haptoglobin genotypes in Chagas' disease.

Clinical biochemistry - 1 Feb 2010

Jorge Susan E D C, Abreu Cristina Feix, Guariento Maria Elena, Sonati Maria de Fatima

Abstract excerpt

OBJECTIVES: To investigate the existence of an association between haptoglobin (Hp) genotypes and the severity of heart complications in Chagas' disease. DESIGN AND METHODS: Hp genotyping was performed by PCR in 107 Brazilian patients sub-classified in asymptomatic, with mild heart disease and with severe heart disease. RESULTS: Multiple logistic regression (R(2)=24%) indicated that patients with the Hp1-1...

Topics

Animals
Brazil
Chagas Cardiomyopathy
Chagas Disease
Genotype
Haptoglobins
Humans
Risk Factors

Source

Open in PubMed

Identifiers

PMID: 19804773
DOI: 10.1016/j.clinbiochem.2009.09.020

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