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Article

Correlation of TcII discrete typing units with severe chronic Chagas cardiomyopathy in patients from various Brazilian geographic regions.

PLoS neglected tropical diseases - 1 Dec 2022

Tavares de Oliveira Maykon, Fuzo Carlos Alessandro, da Silva Maria Cláudia, Donadi Eduardo Antônio, da Silva João Santana, Moreira Henrique Turin, Schmidt André, Marin-Neto José Antônio

Abstract excerpt

BACKGROUND: Chagas disease (ChD) is caused by Trypanosoma cruzi. The genetic structure of the species is divided into seven distinct genetic groups, TcI to TcVI, and Tcbat, which have shown differences in terms of geographic distribution, biological properties, and susceptibility to drugs. However, the association between genetic variability and clinical forms of ChD has not yet been fully elucidated. The...

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Identifiers

PMID: 36508471
DOI: 10.1371/journal.pntd.0010713
PMCID: PMC9794067

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