Article
Hepatitis B precore/core promoter mutations in isolates from HBV-monoinfected and HBV-HIV coinfected patients: a 3-yr prospective study.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Dec 2009
Cassino Lucila, Laufer Natalia, Salomon Horacio, Campos Rodolfo, Quarleri Jorge
Abstract excerpt
BACKGROUND: The course of chronic HBV infection is modified by HIV-coexistence. OBJECTIVE: To analyze the role of HBV genomic heterogeneity in basal core promoter (BCP) and precore (Pc) genomic regions. STUDY DESIGN: In a 3-yr prospective study, 39 HBV infected patients (20 monoinfected and 19 HIV-coinfected) were included. Eighty-two HBV isolates were studied at quasispecies level in the BCP/Pc genomic region....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
