Article
Genetic variability in the precore and core promoter regions of hepatitis B virus strains in Karachi.
BMC gastroenterology - 24 Jul 2006
Abbas Zaigham, Muzaffar Rana, Siddiqui Arif, Naqvi Syed Ali Anwar, Rizvi Syed Adibul Hassan
Abstract excerpt
BACKGROUND: Hepatitis B virus (HBV) genotypes have distinct geographic distribution. Moreover, much genetic variability has been described in the precore (PC) and basal core promoter (BCP) regions of the HBV genome. The local prevalence of HBV genotypes and mutations has not been well studied. The aim of the present study is to determine the prevalence of HBV genotypes and mutations in the PC and BCP region in...
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