Article
Genetic variability of hepatitis C virus in HBV/HCV co-infection and HCV single-infection.
Archives of virology - 1 Feb 2005
De Mitri M S, Morsica G, Cassini R, Bagaglio S, Andreone P, Bianchi G, Margotti M, Bernardi M
Abstract excerpt
To describe the virological profile of HCV in HBV/HCV co-infection, we investigated the variability of HVR-1 and NS5A domains, which may be involved in viral persistence and replication efficiency. We studied 95 patients: 37 with serological markers of HBV/HCV co-infection, 33 with single HBV and 25 with single HCV infection. HVR-1 complexity and NS5A gene variability were respectively explored by means of...
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