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Article

The actin filament cross-linker L-plastin confers resistance to TNF-alpha in MCF-7 breast cancer cells in a phosphorylation-dependent manner.

Journal of cellular and molecular medicine - 1 Jun 2010

Janji Bassam, Vallar Laurent, Al Tanoury Ziad, Bernardin François, Vetter Guillaume, Schaffner-Reckinger Elisabeth, Berchem Guy, Friederich Evelyne, Chouaib Salem

Abstract excerpt

We used a tumour necrosis factor (TNF)-alpha resistant breast adenocarcinoma MCF-7 cell line to investigate the involvement of the actin cytoskeleton in the mechanism of cell resistance to this cytokine. We found that TNF resistance correlates with the loss of cell epithelial properties and the g...

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Identifiers

PMID: 19799649
DOI: 10.1111/j.1582-4934.2009.00918.x
PMCID: PMC3828844

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TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19799649-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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