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Article

Proteomic analysis of tumor necrosis factor-alpha resistant human breast cancer cells reveals a MEK5/Erk5-mediated epithelial-mesenchymal transition phenotype.

Breast cancer research : BCR - 1 Jan 2008

Zhou Changhua, Nitschke Ashley M, Xiong Wei, Zhang Qiang, Tang Yan, Bloch Michael, Elliott Steven, Zhu Yun, Bazzone Lindsey, Yu David, Weldon Christopher B, Schiff Rachel, McLachlan John A, Beckman Barbara S, Wiese Thomas E, Nephew Kenneth P, Shan Bin, Burow Matthew E, Wang Guangdi

Abstract excerpt

INTRODUCTION: Despite intensive study of the mechanisms of chemotherapeutic drug resistance in human breast cancer, few reports have systematically investigated the mechanisms that underlie resistance to the chemotherapy-sensitizing agent tumor necrosis factor (TNF)-alpha. Additionally, the relat...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19087274
DOI: 10.1186/bcr2210
PMCID: PMC2656902

Genes

TNF
CKB
GSTM3
GSTP1
KRT19
KRT8
SNAI2
VIM
ZEB1
CDH1
CDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19087274-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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