Article
Membrane protein location-dependent regulation by PI3K (III) and rabenosyn-5 in Drosophila wing cells.
PloS one - 2 Oct 2009
Abe Masato, Setoguchi Yuka, Tanaka Tsubasa, Awano Wakae, Takahashi Kuniaki, Ueda Ryu, Nakamura Akira, Goto Satoshi
Abstract excerpt
The class III phosphatidylinositol-3 kinase (PI3K (III)) regulates intracellular vesicular transport at multiple steps through the production of phosphatidylinositol-3-phosphate (PI(3)P). While the localization of proteins at distinct membrane domains are likely regulated in different ways, the roles of PI3K (III) and its effectors have not been extensively investigated in a polarized cell during tissue...
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