Article
Different levels of Hoxa2 are required for particular developmental processes.
Mechanisms of development - 1 Oct 2001
Ohnemus S, Bobola N, Kanzler B, Mallo M
Abstract excerpt
Hoxa2 is required for a variety of developmental processes in the branchial arches and in the hindbrain. We have created a Hoxa2 allele that is about 45% as active in transcription as its wild-type counterpart. This allele, together with the Hoxa2 null and wild-type alleles, allowed the generation of embryos developing in the presence of different levels of Hoxa2 activity. Analysis of these embryos indicates that...
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