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Article

A restriction fragment length polymorphism for human topoisomerase II: possible relationship to drug-resistance.

Cancer communications - 1 Jan 1990

Zwelling L A, Mayes J, Deisseroth K, Hinds M, Grant G, Pathak S, Ledley F D, Vyas R, Hittelman W

Abstract excerpt

In previous studies we used Southern blotting to examine the topoisomerase II locus (on chromosome 17) in human leukemia cell lines and noted a difference in the XmnI restriction endonuclease digestion pattern between an m-AMSA-resistant line and its m-AMSA-sensitive parent line (Zwelling, L. A.; Hinds, M,; Chan, D.; Mayes, J.; Sie, K. L.; Parker, E.; Silberman, L.; Radcliffe, A.; Beran, M.; Blick, M....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 1978687
DOI: 10.3727/095535490820874047

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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