A new DNA marker (D10S94) very tightly linked to the multiple endocrine neoplasia type 2A (MEN2A) locus.

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Article

A new DNA marker (D10S94) very tightly linked to the multiple endocrine neoplasia type 2A (MEN2A) locus.

American journal of human genetics - 1 Dec 1990

Goodfellow P J, Myers S, Anderson L L, Brooks-Wilson A R, Simpson N E

Abstract excerpt

Combined somatic cell hybrid and linkage studies between D10S94 and five pericentromeric loci (FNRB, D10Z1, MEN2A, RBP3, and D10S15) have localized the new DNA sequence pcl1/A1S-6-c23 at D10S94 to 10q11.2. No recombinants were observed between D10S94 and D10Z1 or MEN2A. D10S94 maps in proximal 10q11.2 very near to MEN2A. There are three possible orders for the six loci that we investigated from the centromeric...

Topics

Adrenal Gland Neoplasms
Chromosome Mapping
Chromosomes, Human, Pair 10
Cloning, Molecular
Crossing Over, Genetic
DNA
Female
Genetic Linkage
Genetic Markers
Genotype
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Multiple Endocrine Neoplasia

Parathyroid Neoplasms

Pedigree

Pheochromocytoma

Recombination, Genetic

Thyroid Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 1978561
PMCID: PMC1683904

Genes

RBP3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1978561-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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