Identification of a hypervariable microsatellite polymorphism within D9S15 tightly linked to Friedrich's ataxia.

doi:10.1007/BF00276331

Back to search

Article

Identification of a hypervariable microsatellite polymorphism within D9S15 tightly linked to Friedrich's ataxia.

Human genetics - 1 Jun 1990

Wallis J, Williamson R, Chamberlain S

Abstract excerpt

We have identified a hypervariable microsatellite sequence within the chromosome 9 marker MCT112 (D9S15), which we have previously shown to be tightly linked to Friedreich's ataxia (FRDA). The system detects 7 alleles ranging in size from 195 to 209 base pairs, and substantially increases informa...

Topics

Alleles
Base Sequence
Chromosomes, Human, Pair 9
DNA
DNA, Satellite
Friedreich Ataxia
Genetic Linkage
Genetic Markers
Humans
Molecular Sequence Data
Pedigree
Polymerase Chain Reaction
Polymorphism, Genetic

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.