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Advancing therapeutic strategies for Epstein-Barr virus-associated malignancies through lytic reactivation

23 May 2023

Abstract excerpt

Epstein-Barr virus (EBV) is a widespread human herpes virus associated with lymphomas and epithelial cell cancers. It establishes two separate infection phases, latent and lytic, in the host. Upon infection of a new host cell, the virus activates several pathways, to induce the expression of lytic EBV antigens and the production of infectious virus particles. Although the carcinogenic role of latent EBV infection...

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PMID: 37229802
DOI: 10.1016/j.biopha.2023.114916

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