Article
Enduring consequences of early-life infection on glial and neural cell genesis within cognitive regions of the brain.
Brain, behavior, and immunity - 1 Mar 2010
Bland Sondra T, Beckley Jacob T, Young Sarah, Tsang Verne, Watkins Linda R, Maier Steven F, Bilbo Staci D
Abstract excerpt
Systemic infection with Escherichia coli on postnatal day (P) 4 in rats results in significantly altered brain cytokine responses and behavioral changes in adulthood, but only in response to a subsequent immune challenge with lipopolysaccharide [LPS]. The basis for these changes may be long-term...
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