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Article

Heparan sulfate deficiency in periocular mesenchyme causes microphthalmia and ciliary body dysgenesis.

Experimental eye research - 1 Jan 2010

Iwao Keiichiro, Inatani Masaru, Ogata-Iwao Minako, Yamaguchi Yu, Okinami Satoshi, Tanihara Hidenobu

Abstract excerpt

The heparan sulfate (HS) is a component of proteoglycans in the extracellular matrix and on cell surfaces, modulating developmental processes. The aim of this study is to investigate whether the defect of HS in the periocular mesenchyme impairs ocular morphogenesis. First, using Protein 0-Cre tra...

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Source

Identifiers

PMID: 19782070
DOI: 10.1016/j.exer.2009.09.017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19782070-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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