Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of FANCA as a protein interacting with centromere-associated protein E.

Acta biochimica et biophysica Sinica - 1 Oct 2009

Du Jian, Chen Lijian, Shen Jilong

Abstract excerpt

This study sought to isolate and identify proteins that interact with centromere-associated protein E (CENPE), provide new clues for exploring the function of CENP-E in cell cycle control and the pathogenesis of tumor. Yeast two-hybrid screen and regular molecular biologic techniques were undertaken to screen human HeLa cDNA library with the kinetochore binding domain of CENP-E. The bait from the C-terminus of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomal Proteins, Non-Histone
Share to Fanconi Anemia
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glutathione Transferase

Share to HeLa Cells

Share to Protein Interaction Domains and Motifs

Share to Tumor Cells, Cultured

Share to Two-Hybrid System Techniques

Source

Identifiers

PMID: 19779646
DOI: 10.1093/abbs/gmp074

Genes

FANCA
CENPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of FANCA as a protein interacting with centromere-associated protein E.PMID 19779646Read ↗

Centromere Protein F (CENPF) Serves as a Potential Prognostic Biomarker and Target for Human Hepatocellular CarcinomaSemantic proximity Read ↗

Functional complementation of human centromere protein A (CENP-A) by Cse4p from Saccharomyces cerevisiae.Semantic proximity Read ↗

In vivo functional dissection of human inner kinetochore protein CENP-C.Semantic proximity Read ↗

A positive feedback loop of CENPU/E2F6/E2F1 facilitates proliferation and metastasis via ubiquitination of E2F6 in hepatocellular carcinomaSemantic proximity Read ↗

Elevated expression of the centromere protein-A(CENP-A)-encoding gene as a prognostic and predictive biomarker in human cancers.Semantic proximity Read ↗

High expression levels of centromere protein O participates in cell activity of human ovarian cancerSemantic proximity Read ↗

CENPA facilitates hepatocellular carcinoma proliferation by cooperating with YY1 to drive transcription of CCND1 and NRP2.Semantic proximity Read ↗

Activated interferon signaling by down-regulation of CENP-N contributing to inhibited tumor growth in breast cancerSemantic proximity Read ↗

Overexpression of centromere protein K (CENP-K) gene in hepatocellular carcinoma promote cell proliferation by activating AKT/TP53 signal pathwaySemantic proximity Read ↗

Dissection of CENP-C-directed centromere and kinetochore assembly.Semantic proximity Read ↗

Upregulation of centromere protein M promotes tumorigenesis: A potential predictive target for cancer in humans.Semantic proximity Read ↗

CDK1-mediated CENP-C phosphorylation modulates CENP-A binding and mitotic kinetochore localization.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.