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Article

Elevated expression of the centromere protein-A(CENP-A)-encoding gene as a prognostic and predictive biomarker in human cancers.

International journal of cancer - 15 Aug 2016

Sun Xia, Clermont Pier-Luc, Jiao Wenlin, Helgason Cheryl D, Gout Peter W, Wang Yuzhuo, Qu Sifeng

Abstract excerpt

Centromere protein-A (CENP-A), a histone-H3 variant, plays an essential role in cell division by ensuring proper formation and function of centromeres and kinetochores. Elevated CENP-A expression has been associated with cancer development. This study aimed to establish whether elevated CENP-A expression can be used as a prognostic and predictive cancer biomarker. Molecular profiling of CENP-A in human cancers...

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PMID: 27062469
DOI: 10.1002/ijc.30133

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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