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Article

New real-time PCR-based method for the joint genotyping of JAK2 (V617F) with inherited thrombophilic F5 and F2 mutations.

Clinica chimica acta; international journal of clinical chemistry - 1 Dec 2009

Martínez-Serra J, Maffiotte E, Gutierrez A, Durán M A, Amat J C, Besalduch J

Abstract excerpt

BACKGROUND: During the last years the appearance of the acquired V617F mutation of the Janus Kinase 2 gene (JAK2) in patients suffering different thrombotic events has been described. We decided to develop a new and rapid multiplex real-time Polymerase Chain Reaction (PCR) in order to detect the V617F mutation together with the inherited prothrombotic mutations of factors F5 and F2. DESIGN AND METHODS: The method...

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Source

Identifiers

PMID: 19778528
DOI: 10.1016/j.cca.2009.09.022

Genes

JAK2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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