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Article

Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 2.

Journal of medicinal chemistry - 18 Nov 2004

Freeman George A, Andrews Iii C Webster, Hopkins Andrew L, Lowell Gina S, Schaller Lee T, Cowan Jill R, Gonzales Stephen S, Koszalka George W, Hazen Richard J, Boone Lawrence R, Ferris Rob G, Creech Katrina L, Roberts Grace B, Short Steven A, Weaver Kurt, Reynolds David J, Milton John, Ren Jingshan, Stuart David I, Stammers David K, Chan Joseph H

Abstract excerpt

HIV-1 nonnucleoside reverse transcriptase inhibitors (NNRTIs) are part of the combination therapy currently used to treat HIV infection. The features of a new NNRTI drug for HIV treatment must include selective potent activity against both wild-type virus as well as against mutant virus that have...

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PMID: 15537347
DOI: 10.1021/jm040072r

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15537347-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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