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Adoptive immunotherapy for cancer: the next generation of gene‐engineered immune cells

17 Sept 2009

Abstract excerpt

Adoptive cellular immunotherapy involving transfer of tumor-reactive T cells has shown some notable antitumor responses in a minority of cancer patients. In particular, transfer of tumor-infiltrating lymphocytes has resulted in long-term objective responses in patients with advanced melanoma. However, the inability to isolate sufficient numbers of tumor-specific T cells from most malignancies has restricted the...

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PMID: 19775368
DOI: 10.1111/j.1399-0039.2009.01336.x

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