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Genetically engineered T cells for cancer immunotherapy

19 Sept 2019

Abstract excerpt

T cells in the immune system protect the human body from infection by pathogens and clear mutant cells through specific recognition by T cell receptors (TCRs). Cancer immunotherapy, by relying on this basic recognition method, boosts the antitumor efficacy of T cells by unleashing the inhibition of immune checkpoints and expands adaptive immunity by facilitating the adoptive transfer of genetically engineered T...

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PMID: 31637014
DOI: 10.1038/s41392-019-0070-9

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