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Article

Methylation status of the APC and RASSF1A promoter in cell-free circulating DNA and its prognostic role in patients with colorectal cancer

1 Jun 2016

Abstract excerpt

DNA methylation is the most frequent epigenetic alteration. Using methylation-specific polymerase chain reaction (MSP), the methylation status of the adenomatous polyposis coli (APC) and Ras association domain family 1 isoform A (RASSF1A) genes was examined in cell‑free circulating DNA from 155 plasma samples obtained from patients with early and advanced colorectal cancer (CRC). APC and RASSF1A hypermethylation...

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Share to Cancer-related gene regulation
Share to Epigenetics and DNA Methylation
Share to Genetic factors in colorectal cancer

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PMID: 27347211
DOI: 10.3892/ol.2016.4649

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