Association of polymorphisms in TNF and GRN genes with ankylosing spondylitis in a Chinese Han population.

doi:10.1007/s00296-017-3899-7

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Article

Association of polymorphisms in TNF and GRN genes with ankylosing spondylitis in a Chinese Han population.

Rheumatology international - 1 Mar 2018

Hu Naiwen, Cui Yazhou, Yang Qingrui, Wang Liya, Yang Xinglin, Xu Hongzhi

Abstract excerpt

The aim of this study is to investigate the association of the polymorphisms in tumor necrosis factor (TNF) and granulin (GRN) with ankylosing spondylitis (AS) in a Chinese Han population. Five single nucleotide polymorphisms (SNPs) covering TNF and six SNPs covering GRN were investigated in 861 Chinese Han AS patients and 864 healthy controls. For rs1799964, the C allele was linked to reduced risk of AS...

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PMID: 29230494
DOI: 10.1007/s00296-017-3899-7

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