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Article

[The impact of the HIV-1 envelope (Env) mutation on its assembly of functional pseudovirus].

Bing du xue bao = Chinese journal of virology - 1 Jul 2009

Wang Su-Ting, Nie Jian-Hui, Chong Hui-Hui, Zhang Chun-Tao, Wu Xue-Ling, Wang You-Chun

Abstract excerpt

To find out whether the mutations of HIV-1 Env have influence on the assembly of pseudovirus and their abilities to infect cells, site-directed mutation (A457D)was performed using cycling mutagenesis and selection of mutants with DpnI. Transformation and plasmid purification technologies were used to obtain mutated env clone. Then both the prototype and the mutant were co-transfected with pSG3(delta(env)) to...

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Identifiers

PMID: 19769157

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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