Article
[What's going on post-budding?].
Uirusu - 1 Jun 2011
Sakuragi Jun-ichi
Abstract excerpt
In general, the retrovirus particles become infectious on post-budding with cleavages of structural protein Gag by viral protease. Protease defective mutants bud particles normally, but the particles are non-infectious and called donuts-like particle because of their morphology. The viral genomes inside the donuts-like particles form very fragile dimer, which are far different from those in wild-type particles....
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