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Article

Post-transplantation malignancy: a cell autonomous mechanism with implications for therapy.

Transactions of the American Clinical and Climatological Association - 1 Jan 2009

Suthanthiran Manikkam, Hojo Minoru, Maluccio Mary, Boffa Daniel J, Luan Fu L

Abstract excerpt

Malignancy is a dreaded complication following organ transplantation. Immunosuppressive therapy-induced impairment of the host immune system is the prevailing hypothesis for the high incidence and aggressive progression of post-transplant neoplasm. We summarize our observations supporting an autonomous cellular mechanism for cyclosporine and tacrolimus associated metastases. Cyclosporine conferred tumor...

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Identifiers

PMID: 19768190
PMCID: PMC2744527

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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