Article
Association of TP53 and MDM2 polymorphisms with survival in bladder cancer patients treated with chemoradiotherapy.
Cancer science - 1 Dec 2009
Shinohara Asano, Sakano Shigeru, Hinoda Yuji, Nishijima Jun, Kawai Yoshihisa, Misumi Taku, Nagao Kazuhiro, Hara Takahiko, Matsuyama Hideyasu
Abstract excerpt
Platinum-based chemoradiotherapy (CRT) as bladder conservation therapy has shown promising results for muscle-invasive bladder cancer. However, CRT might diminish survival as a result of the delay in cystectomy for some patients with non-responding bladder tumors. Because the p53 tumor suppressio...
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