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Article

Significance of TP53 mutation in bladder cancer disease progression and drug selection

16 Dec 2019

Abstract excerpt

BACKGROUND: The tumor protein p53 (TP53) mutant is one of the most frequent mutant genes in bladder cancer. In this study, we assessed the importance of the TP53 mutation in bladder cancer progression and drug selection, and identified potential pathways and core genes associated with the underlying mechanisms. METHODS: Gene expression data used in this study were downloaded from The Cancer Genome Atlas and...

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PMID: 31871844
DOI: 10.7717/peerj.8261

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