Article
Candidate gene association analysis.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2009
Singer Jonathan B
Abstract excerpt
Candidate gene association study is the most common method for associating human genetic variations with the phenotypes they produce, due to the relative simplicity of acquiring patient samples and genotype data. The study design begins with identifying appropriate DNA samples and an appropriate phenotype for analysis. The candidate genes and polymorphisms must then be chosen. After genotyping the candidate genes...
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