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Article

Focal brain malformations: seizures, signaling, sequencing.

Epilepsia - 1 Oct 2009

Crino Peter B

Abstract excerpt

Focal malformations of cortical development are highly associated with intractable epilepsy in children and adults. Most patients with focal cortical malformations and epilepsy will require epilepsy surgery. Recent studies have provided new insights into the developmental pathogenesis of cortical malformations specifically relating to alterations in cell signaling though the mammalian target of rapamycin (mTOR)...

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Identifiers

PMID: 19761448
DOI: 10.1111/j.1528-1167.2009.02289.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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