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Article

Evidence for limited genetic compartmentalization of HIV-1 between lung and blood.

PloS one - 14 Sept 2009

Heath Laura, Fox Alan, McClure Jan, Diem Kurt, van 't Wout Angélique B, Zhao Hong, Park David R, Schouten Jeffrey T, Twigg Homer L, Corey Lawrence, Mullins James I, Mittler John E

Abstract excerpt

BACKGROUND: HIV-1 is frequently detected in the lungs of infected individuals and is likely important in the development of pulmonary opportunistic infections. The unique environment of the lung, rich in alveolar macrophages and with specialized local immune responses, may contribute to differential evolution or selection of HIV-1. METHODOLOGY AND FINDINGS: We characterized HIV-1 in the lung in relation to...

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Identifiers

PMID: 19759830
DOI: 10.1371/journal.pone.0006949
PMCID: PMC2736399

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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