Distribution of HLA class II alleles among Scandinavian patients with systemic lupus erythematosus (SLE): an increased risk of SLE among non[DRB1*03,DQA1*0501,DQB1*0201] class II homozygotes?

doi:10.1111/j.1399-0039.1992.tb02104.x

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Article

Distribution of HLA class II alleles among Scandinavian patients with systemic lupus erythematosus (SLE): an increased risk of SLE among non[DRB103,DQA10501,DQB1*0201] class II homozygotes?

Tissue antigens - 1 Sept 1992

Skarsvåg S, Hansen K E, Holst A, Moen T

Abstract excerpt

HLA-DRB1, -DRB3, -DQA1 and -DQB1 alleles were determined by DNA typing in 51 Scandinavian patients with systemic lupus erythematosus (SLE) and 129 controls. DRB1*03,DRB3*0101,DQA1*0501,DQB1*0201 were significantly increased in the patient group, with relative risks (RR) of 2.80, 3.07, 3.55 and 2.12, respectively. These alleles are in strong linkage disequilibrium, and their possible relative contributions in...

Topics

Adolescent
Adult
Aged
Autoimmune Diseases
Base Sequence
Disease Susceptibility
Female
Genes, MHC Class II
Genetic Predisposition to Disease
HLA-DQ Antigens
HLA-DQ beta-Chains

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

HLA-DR Antigens

HLA-DRB1 Chains

Histocompatibility Antigens Class II

Homozygote

Humans

Lupus Erythematosus, Systemic

Male

Source

Open in PubMed

Identifiers

PMID: 1440567
DOI: 10.1111/j.1399-0039.1992.tb02104.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1440567-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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