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Article

Val/Leu247 polymorphism of beta2-glycoprotein I in Brazilian patients with antiphospholipid syndrome--a genetic risk factor?

Annals of the New York Academy of Sciences - 1 Sept 2009

Pernambuco-Climaco Juliana M, Brochado Maria Jose F, Freitas Max Victor C, Roselino Ana Maria F, Louzada-Junior Paulo

Abstract excerpt

A genetic polymorphism of the beta2-glycoprotein I (beta2-GPI) is recognized by antiphospholipid antibodies (aPL) and may even play a role in the development of antiphospholipid syndrome (APS). The objectives of this study were to determine a Val/Leu SNP at position 247 of the beta2-GPI gene in Brazilian patients with APS and to compare these data with clinical and laboratory manifestations. Polymorphism...

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Source

Identifiers

PMID: 19758193
DOI: 10.1111/j.1749-6632.2009.04655.x

Genes

GPI

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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